On October 1909 the community of Sisters of Mercy came from Mytilene to Kavala and found the newly constructed priory ready for habitation with the Gothic chapel of St. Joseph, in which the school was dedicated, which operated under the management of Lady Margaret. The building was renewed after the six-year “exile” of the community because of the World War I and continued until its withdrawal from Kavala in 1981. Due to serious problems during two years of the Balkan wars in 1912-1913 the school was forced to discontinue its operation and reopened in 1924 only to suspend its services again in 1931-1932 because of the debilitating legislation of the Ministry of Education about the private and therefore Catholic education. It permanently closed in 1981. Cause of this unpleasant, for Kavala, event was the inadequacy of personnel due to the reduction of Brothers in France, which supplied the Catholic mission in Greece and Turkey. The same happened twenty years later in Thessaloniki. The sisters did charity, helped poor families in strict confidence. The French school adapted to each era, offering the students an opportunity to form a complete picture of the society, therefore strictness. The exodus caused sadness to all who knew and loved, because these schools acted as a means of dissemination of traditional values but also as a means of awareness young girls. For 60 years these women had a beneficial presence in the city and its people.